Jason Randall

Jason Randall is a husband, father, U.S. Navy veteran, and stage 4 colorectal cancer survivor. At just 35 years old, while working as a GIS Analyst and Cartographer, Jason began experiencing symptoms that led to a CT scan. The results were devastating: a fully blocked rectosigmoid junction and metastatic disease covering 80% of his liver. He was told his cancer was inoperable and that he would need chemotherapy for life. At the time of his diagnosis, Jason’s wife was still pregnant with their third child, making the news even more crushing for their young family.

In the first 18 months after his diagnosis, Jason endured 30 rounds of chemotherapy and two Y90 procedures targeting his liver. Despite responding well to treatment, his prognosis remained grim—until he sought a second opinion from Dr. Yuman Fong and Dr. Andreas Kaiser at City of Hope in Los Angeles. In a groundbreaking 12-hour surgery, Jason’s liver and colon were operated on with curative intent, shifting the trajectory of his prognosis.

Just five months after surgery, Jason faced a recurrence in his tailbone, leading to four more systemic chemotherapy cycles, 28 full pelvic radiation sessions, and a major APR surgery that removed his remaining rectum, anus, tailbone, and part of the sacrum, leaving him with a permanent colostomy. The surgery succeeded in returning Jason to NED (No Evidence of Disease) for 11 months, though he would later battle additional recurrences in his lung and hilar node area. Each time, Jason’s resilience and cutting-edge treatments—including ablation and SABR (stereotactic ablative radiotherapy)—brought him back to NED, most recently for the fourth time.

Jason first joined Man Up to Cancer in 2020 and quickly became an integral part of the leadership team, serving as an admin and helping launch the organization’s nonprofit arm. In addition to his work with MUTC, Jason also serves on the leadership cabinet of COLONTOWN, providing support and guidance to others in the colorectal cancer community.

Jason and his family recently relocated to the Big Island of Hawai’i, where they are building a small cancer retreat space—a reflection of their commitment to giving back and helping others navigate the challenges of cancer with strength and hope.